B&B Publications

Refereed Journal Articles

The database below lists the refereed journal articles that have emerged from the Biomarkers and Bioinformatics (B&B) Enabling Platform.

The database can be sorted and/or searched by different data fields. When searching by author, use last name only.

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Adamko DJ, Khamis MM, Steacy LM, Regush S, Bryce R, Ellis AK. 2018

Severity of Allergic Rhinitis Assessed by Urine Metabolomic Profiling: Proof of Concept

Journal of Allergy and Clinical Immunology

Oluwole O, Rennie DC, Senthilselvan A, Dyck R, Afanasieva A, Adamko DJ, Lawson JA. 2018

Asthma diagnosis among children along an urban-rural gradient

Journal of Asthma

To T, Bouchard J, Boulet L-P, Brozek J, Denburg A, Schunemann H, Simons FER, Waserman S, Keith PK, Agache I, Bachert C, Bedbrook A, Canonica GW, Casale T, Cruz AA, Fokkens WJ, Hellings PW, Samolinski B, Bousquet J. 2018

ARIA 2016 executive summary: Integrated care pathways for predictive, preventive and personalized medicine across the life cycle

Canadian Journal of Respiratory, Critical Care, and Sleep Medicine

Ma Y, Dawicki W, Zhang X, Gordon JR 2018

Contributions of direct versus indirect mechanisms for regulatory dendritic cell suppression of asthmatic B cell responses


Bernatchez E, Gold MJ, Langlois A, Blais-Lecours P, Boucher M, Duchaine C, Marsolais D, McNagny KM, Blanchet MR 2017

Methanosphaera stadtmanae induces a type IV hypersensitivity response in a mouse model of airway inflammation

Physiological Reports

Markland A, Hansen G, Banks A, Chibbar R, Adamko D. 2017

A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis

Case Reports in Critical Care

Hellings PW, et al. 2017

Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA‐ARIA‐EPOS‐AIRWAYS ICP statement


Dooley D, Griffiths E, Gosal G, Brinkman F, Hsiao W. 2017

The Genomic Epidemiology Ontology and GEEM Ontology Reusability Platform


Lambert D, Pightling A, Griffiths E, Van Domselaar G, Evans P, Berthelet S, Craig D, Chandry PS, Stones R, Brinkman F, Angers-Loustau A, Kreysa J, Tong W, Blais B. 2017

Baseline Practices for the Application of Genomic Data Supporting Regulatory Food Safety

Ingenta Connect

Tworek D, Heroux D, O'Byrne S, Mitchell P, O'Byrne P, Denburg J. 2017

Toll-like receptor-induced expression of epithelial cytokine receptors on haemopoietic progenitors is altered in allergic asthma

Clinical & Experimental Allergy

Ritz T, Rosenfield D, St. Laurent CD, Trueba AF, Werchan CA, Vogel PD, Auchus RJ, Reyes-Serratos E, Befus AD 2017

A novel biomarker associated with distress in humans – calcium binding protein, spermatid specific 1 (CABS1)

Khamis MM, Adamko DJ, El-Aneed A. 2017

Development of a validated LC- MS/MS method for the quantification of 19 endogenous asthma/COPD potential urinary biomarkers

Analytica Chimica Acta

Chen R, Smith SG, Salter B, El-Gammal A, Oliviria JP, Obminski C, Watson R, O'Byrne PM, Gauvreau GM, Sehmi R. 2017

Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma

American Journal of Respiratory and Critical Care Medicine

Skappak C, Ilarraza R, Wu Y-q, Drake MG, Adamko DJ. 2017

Virus-induced asthma attack: The importance of allergic inflammation in response to viral antigen in an animal model of asthma


Yang CX, Singh A, Kim YW, Carlsten C, Tebbutt SJ. 2017

Diagnosis of western red cedar asthma using a blood-based gene expression biomarker panel

American Journal of Respiratory and Critical Care Medicine

Kim YW, Singh A, Shannon CP, Thiele J, Steacy LM, Ellis AK, Neighbour H, Gliddon D, Hickey P, Larché M, Tebbutt SJ. 2017

Investigating immune gene signatures in peripheral blood from subjects with allergic rhinitis undergoing nasal allergen challenge

Journal of Immunology

Lo BC, Gold MJ, Scheer S, Hughes MR, Cait J, Debruin E, Chu FSF, Walker DC, Soliman H, Rossi FM, Blanchet M-R, Perona-Wright G, Zaph C, McNagny KM 2017

Loss of Vascular CD34 Results in Increased Sensitivity to Lung Injury

American Journal of Cell Molecular Biology

Cait A, Hughes MR, Antignano F, Cait J, Dimitriu PA, Maas KR, Reynolds LA, Hacker L, Mohr J, Finlay BB, Zaph C, McNagny KM, Mohn WW 2017

Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids

Mucosal Immunology

Griffiths E, Dooley D, Graham M, Van Domselaar G, Brinkman F, Hsiao W. 2017

Context Is Everything: Harmonization of Critical Food Descriptors and Metadata for Improved Food Safety and Surveillance

Frontiers in Microbiology

Adamko DJ, Saude E, Bear M, Regush S, Robinson J. 2016

Urine metabolomic profiling of children with respiratory tract infections in the emergency department: a pilot study

BMC Infectious Diseases

Batool T, Reece PL, Schulze KM, Morrison KM, Atkinson SA, Anand SS, Teo KK, Denburg JA, Cyr MM, FAMILY Study investigators 2016

Prenatal and early-life predictors of atopy and allergic disease in Canadian children: results of the Family Artherosclerosis Monitoring in earLY life (FAMILY) Study

Journal of Developmental Origins of Health and Disease

Hörnig F, Kohajda T, Röder S, Herberth G, von Bergen M, Borte M, Diez U, Rolle-Kampczyk U, Simon JC, Denburg JA, Lehmann I, Junge KM. 2016

The LINA study: higher sensitivity of infant compared to maternal eosinophil/basophil progenitors to indoor chemical exposures.

Journal of Environmental Public Health

Chow LN, Schreiner P, Lo B, Gusti V, Lecour S, Bara I, Scott W, Webb M, McNagny KM, Crawford J, Underhill M. 2016

Impact of a CXCL12/CXCR4 antagonist in bleomycin (BLM) induced pulmonary fibrosis and carbon tetrachloride (CCl4) induced hepatic fibrosis in mice


McKay KA, Kowalec K, Brinkman F, Finlay BB, Horwitz M, Manges AR, Osborne L, Tremlett H. 2016

From bugs to brains: The microbiome in neurological health

Multiple Sclerosis and Related Disorders

Gold MJ, Antignano F, Hughes MR, Zaph C, McNagny KM 2016

Dendritic-cell expression of Ship1 regulates Th2 immunity to helminth infection in mice

European Journal of Immunology

Siemerink MJ, Hughes RM, Gora T, Dallinga M, Vogels IMC, Van Noorden CJF, Klaassen I, McNagny KM, Schlingemann RO. 2016

CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy


Antignano F, Braam M, Hughes MR, Burrows K, Chenery A, Gold MJ, Oudhoff MJ, Rattray D, Halim T, Takei F, Rossie FMV, McNagny KM, Zaph C. 2016

G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell development program

Journal of Experimental Medicine

Lo B, Gold MJ, Hughes MR, Antignano F, Zaph C, Harder KW, McNagny KM 2016

The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn’s disease

Science Immunology

Hui CCK, McNagny KM, Denburg JA, Siracusa MC. 2015

In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces

Mucosal Immunology

Gold MJ, Hughes MR, Antignano F, Hirota JA, Zaph C,McNagny KM. 2015

Lineage-specific regulation of allergic airway inflammation by the lipid phosphatase Src homology 2 domain-containing inositol 5-phosphatase (SHIP-1)

Journal of  Allergy and Clinical Immunology

Bernatchez E, Gold MJ, Langlois A, Lemay A-M, Brassard J, Flamand N, Marsolais D,McNagny KM, Blanchet M-R. 2015

Pulmonary CD103 expression regulates airway inflammation in asthma

American Journal of Physiology – Lung Cellular and Molecular Physiology

Adamko D, Nair P, Mayers I, Tsuyuki R, Regush S, Rowe B 2015

Metabolomic profiling of asthma and chronic obstructive pulmonary disease: A pilot study differentiating diseases

Journal of Allergy and Clinical Immunology

Khamis M, Adamko D, El-Aneed A. 2015

Mass Spectrometric Based Approaches in Urine Metabolomics and Biomarker Discovery

Mass Spectrometry Reviews

St. Laurent CD, St. Laurent K, Mathison RD, Befus AD. 2015

Calcium binding spermatid-specific 1 is expressed in human salivary glands and contains a protein motif with anti-inflammatory activity

American Journal of Physiology – Regulatory, Integrative and Comparative Physiology

Laird MR, Langille MG, Brinkman FS 2015

GenomeD3Plot: A library for rich, interactive visualizations of genomic data in web applications


Xu J, Singhera GK, Dorscheid DR. 2015

Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium

Respiratory Research

Frias S, Bryan K,Brinkman FSL, Lynn DJ. 2015

CerebralWeb: a Cytoscape.js plug-in to visualise networks stratified by subcellular localization

Database (Oxford)

Ajamian F, Wu Y, Ebeling C, Ilarraza R, Odemuyiwa SO, Moqbel R, Adamko DJ. 2015

Respiratory syncytial virus induces indoleamine 2,3-dioxygenase activity: a potential novel role in the development of allergic disease

Clinical & Experimental Allergy

Junge KM, Hörnig F, Herberth G, Röder S, Kohajda T, Rolle-Kampczyk U, von Bergen M, Borte M, Simon JC, Heroux D, Denburg JA,Lehmann I. 2014

The LINA Cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy

Clinical Immunology

Daley D 2014

The evolution of the hygiene hypothesis: the role of early-life exposures to viruses and microbes and their relationship to asthma and allergic disease

Current Opinion in Allergy and Clinical Immunology

Simpson CL, Goldenberg AJ, Culverhouse R, Daley D, Igo Jr. RP, Jarvick GP, Mandal DM, Mascalzoni D, Montgomery CG, Pierce B, Plaetke R, Shete S, Goddard KAB, Stein CM. 2014

Practical Barriers and Ethical Challenges in Genetic Data Sharing

International Journal of Environmental Research and Public Health

Ring J, Akdis C, Lauener R, Schäppi G, Traidl-Hoffmann C, Akdis M, Ammann W, Behrendt H, Bieber T, Biedermann T, Bienestock J, Blaser K, Braun-Fahrländer C, Brockow K, Buters J, Crameri R, Darsow U, Denburg JA, Eyerich K, Frei R, Galli SJ, Gutermuth J, 2014

Global Allergy Forum and Second Davos Declaration 2013 Allergy: Barriers to cure – challenges and actions to be taken


Aloyouni SY, Segeritz CP, Sharrid A, Gold MJ, Loeffler DIM, Blanchet M-R, Cai B, Hirota J, McNagny KM, Kollmann TR. 2014

Perinatal immunization with vaccine-grade Listeria monocytogenes provies long-term protection against murine Th2 airway inflammation

Hui C, Murphy D, Neighbour H, Al-Sayegh M, O?Byrne S, Thong B, Denburg J, Larche M. 2014

T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells

Clinical & Experimental Allergy

Reece P, Gauvreau GM, Sehmi R, Denburg JA. 2014

IL-4 and IL-13 differentially regulate TLR-induced eosinophil-basophil differentiation of cord blood CD34+ progenitor cells


Hui CCK, Rusta-Sallehy S, Asher I, Heroux D, Denburg JA. 2014

The effects of thymic stromal lymphopoietin and IL-3 on human eosinophil-basophil lineage commitment: relevance to atopic sensitization

Immunity Inflammation and Disease

Gold MJ, Antignoano F, Halim TYF, Hirota JA, Blanchet M-R, Zaph C, Takei F, McNagny KM. 2014

Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures

Journal of Allergy and Clinical Immunology

Scholtens S, Postma DS, Moffatt MF, Panasevich S, Granell R, Henderson AJ, Melén E, Nyberg F, Pershagen G, Jarvis D, Ramasamy A, Wjst M, Svanes C, Bouzigon E, Demenais F, Kauffmann F, Siroux V, von Mutius E, Ege MJ, Braun-Fahrländer C, Genuneit J; GABRI 2014

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure

Journal of Allergy and Clinical Immunology

Singh A, Yamamoto M, Ruan J, Young Choi J, Gauvreau GM, Olek S, Hoffmueller U, Carlsten C, FitzGerald JM, Boulet L-P, O'Byrne PM, Tebbutt SJ. 2014

Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response

Allergy, Asthma & Clinical Immunology

Blanchet M-R, Gold M, McNagny K. 2014

Mutant Mice and Animal Models of Airway Allergic Diseases

Methods in Molecular Biology: Eosinophils – Methods and Protocols

Peng J, St. Laurent CD, Befus AD, Zhou R, Li L. 2014

Metabolomic profiling of bronchoalveolar lavage fluids by isotope labeling liquid chromatography mass spectrometry: a promising approach to studying experimental asthma


O'Doherty KC, Neufeld JD, Brinkman FSL, Gardner H, Guttman DS, Beiko RG. 2014

Opinion: Conservation and stewardship of the human microbiome

Proceedings of the National Academy of Sciences USA

Meulien P, Brinkman FSL, Gardy JL. 2014

Big Ideas, Big Data: How genomics will change our world

Policy Magazine

Allakhverdi Z, Comeau MR, Armant M, Agrawal, Woodfolk JA, Sehmi R, Howie KJ, Gauvreau G, Delespesse G. 2013

Mast Cell-Activated Bone Marrow Mesenchymal Stromal Cells Regulate Proliferation and Lineage Commitment of CD34(+) Progenitor Cells

Frontiers in Immunology

Reece P, Baatjes AJ, Cyr MM, Sehmi R, Denburg JA. 2013

Toll-like receptor-mediated eosinophil-basophil differentiation: autocrine signalling by granulocyte-macrophage colony-stimulating factor in cord blood haematopoiectic


Foroushani AB, Brinkman FS, Lynn DJ. 2013

Pathway-GPS and SIGORA: identifying relevant pathways based on the over-representation of their gene-pair signatures


Singh A, Yamamoto M, Kam SHY, Ruan J, Gauvreau GM, O'Byrne PM, FitzGerald JM, Schellenberg R, Boulet L-P, Wojewodka G, Kanagaratham C, De Sanctis J, Radzioch D, Tebbutt SJ. 2013

Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses


Hsu K, Turvey S. 2013

Functional analysis of the impact of ORMDL3 expression on inflammation and activation of the unfolded protein response in human airway epithelial cells

Allergy, Asthma & Clinical Immunology

Azad MB, Konya T, Maughan H, Guttman DS, Field CJ, Chari RS, Sears MR, Becker AB, Scott JA, Kozyrskyj AL, CHILD Study Investigators. 2013

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months

Canadian Medical Association Journal

Cho P, Gelinas L, Corbett NP, Tebbutt SJ, Turvey SE, Fortuno III ES, Kollmann TR. 2013

Association of common single nucleotide polymorphisms in innate immune genes with TLR-induced cytokine production in neonates

Genes & Immunity

Ali S, Hirschfeld AF, Mayer ML, Fortuno ES, Corbett N, Schneiderman J, Fjell CD, Hsu K, Marr N, Yan J Akhabir L, Aminuddin F, Lacaze-Masmonteil T, Hegele RG, Becker A, Chan-Yeung M, Hancock REW, Kollmann TR, Daley D, Sandford AJ, Lavoie PM, Turvey SE 2013

Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis and bronchopulmonary dysplasia

The Journal of Immunology

Scherberich S, Di Maggio N, McNagny KM. 2013

A familiar stranger: CD34 expression and putative functions in SVF cells of adipose tissue

World Journal of Stem Cells

Russell SL, Gold MJ, Willing BP, Thorson L, McNagny KM, Finlay BB. 2013

Perinatal antibiotic treatment affects murine microbiota, immune responses and allergic asthma

Gut Microbes

del-Toro N, Dumousseau M, Orchard S, Jimenez R, Galeota E, Launay G, Goll J, Breuer K, Ono K, Salwinski L, Hermjakob H. 2013

A New Reference Implementation of the PSICQUIC web service

Nucleic Acids Research

Breuer K, Foroushani AK, Laird MR, Chen C, Sribnaia A, Lo R, Winsor GL, Hancock RE, Brinkman FS, Lynn DJ. 2013

InnateDB: systems biology of innate immunity and beyond–recent updates and continuing curation

Nucleic Acids Research

Mullaly SC, Oudhoff MJ, Min PH, Burrows K, Antignano F, Rattray DG, Chenery A, McNagny KM, Ziltener HJ, Zaph C. 2013

Requirement for core 2 o-glycans for optimal resistance to helminth infection


Ilarraza R, Wu Y, Skappak CD, Ajamian F, Proud D, Adamko DJ. 2013

Rhinovirus Has The Unique Ability To Directly Activate Human T Cells In Vitro

Journal of Allergy and Clinical Immunology

Skappak D, Regush S, Chung P-Y, Adamko DJ. 2013

Identifying hypoxia in a fetal piglet model using urinary NMR metabolomic profiling


Mathison RD, Davison J, St. Laurent CD, Befus AD. 2012

Autonomic regulation of anti-inflammatory activities from salivary glands

Chemical Immunology and Allergy

Russell SL, Gold MJ, Hartmann M, Willing BP, Thorson L, Wlodarska M, Gill N, Blanchet M-R, Mohn WW, McNagny KM. 2012

Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma

European Molecular Biology Organization Reports

Achtman AH, Pilat S, Law CW, Lynn DJ, Janot L, Mayer M, Ma S, Kindrachuck J, Finlay BB, Brinkman FSL, Smyth GK, Hancock REW, Schofield L. 2012

Effective adjunctive therapy by an innate defense regulatory peptide in pre-clinical model of severe malaria

Science Translational Medicine

Levin AM, Mathias RA, Huang L, Roth LA, Daley D, Myers RA, Himes BE, Romieu I,Yang M, Eng C, Park JE, Zoratti K, Gignoux CR, Torgerson DG, Galanter JM, Huntsman S, Nguyen EA, Becker AB, Chan-Yeung M, Kozyrskyj AL, Kwok PY, Gilliland FD, Gauderman WJ, Bl 2012

A Meta-analysis of Genome-wide Association Studies for Serum Total lgE in Diverse Study Populations

Journal of Allergy and Clinical Immunology

Daley D, Park JE, He JQ, Yan J, Akhabir L, Stefanowicz D, Becker AB, Chan-Yeung M, Bossé Y, Kozyrskyj AL, James AL, Musk AW, Laprise C, Hegele RG, Paré PD, Sandford AJ. 2012

Associations and Interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes

Journal of Allergy and Clinical Immunology

Allakhverdi Z, Delespesse G. 2012

Hematopoietic progenitor cells are innate Th2 cytokine-reproducing cells


Maltby S, DeBruin EJ, Bennett J, Gold MJ, Tunis MC, Jian Z, Marshall JS, McNagny KM. 2012

IL-7Rα and L-selectin, but not CD103 or CD34, are required for murine peanut-induced anaphylaxis

Allergy, Asthma & Clinical Immunology

Ilarraza R, Wu Y, Adamko DJ. 2012

Montelukast inhibits leukotriene stimulation of human dendritic cells in vitro

International Archives of Allergy and Immunology

Weiße K, Lehmann I, Heroux D, Kohajda T, Herberth G, Roder S, von Bergen M, Borte M, Denburg J. 2012

The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/b) progenitors and early life skin manifestations

Clinical & Experimental Allergy

Cruz-Sanchez TM, Haddrell AE, Hackett TL, Singhera GK, Marchant D, Lekivetz R, Meredith A, Horne D, Knight DA, van Eeden SF, Bai TR, Hegele RG, Dorscheid DR, Agnes GR. 2012

Formation of a Stable Mimic of Amient Particulate Matter Containing Viable Infectious Respiratory Syncytial Virus and Its Driy-Deposition Directly onto Cell Cultures

Analytical Chemistry

Blanchet M-R, Gold MJ, McNagny KM. 2012

Mouse models to evaluate the function of genes associated with allergic airway disease

Current Opinion in Allergy and Clinical Immunology

Wakahara K, Van VQ, Baba N, Begin P, Rubio M, Delespesse G, Sarfati M. 2012

Basophils are recruited to inflamed lungs and exacerbate memory Th2 responses in mice and humans


Wakahara K, Baba N, Van VQ, Bégin P, Rubio M, Ferraro P, Panzini B, Wassef R, Lahaie R, Caussignac Y, Tamaz R, Richard C, Soucy G, Delespesse G, Sarfati M. 2012

Human basophils interact with memory T cells to augment Th17 responses


Karimi K, Kandiah N, Chau J, Bienenstock J, Forsythe P. 2012

A Lactobacillus rhamnosus strain induces a heme oxygenase dependent increase in Foxp3+ regulatory T cells


Melén E, Granel Rl, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D, Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch NM, Curjuric I, Imbode 2012

Genome-wide association study of body mass index in 23,000 individuals with and without asthma

Clinical & Experimental Allergy

Halim TY, MacLaren A, Romanish MT, Gold MJ, McNagny KM, Takei F. 2012

Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation


Alton ME,Tough SC, Mandhane PJ, Kozyrskyj AL. 2012

Street drug use during pregnancy: potential programming effects on preschool wheeze

Journal of Developmental Origins of Health and Disease

Adamko DJ, Sykes BD, Rowe BH . 2012

The metabolomics of asthma: novel diagnostic potential


Reece P, Thanendran A, Crawford L, Prescott SL, Sehmi R, Denburg JA. 2011

Maternal allergy modulates cord blood hemopoietic progenitor Toll-like receptor expression and function

Journal of Allergy and Clinical Immunology

Suace DJ, Skappak C, Regus S, Cook K, Ben-Zvi A, Becker A, Moqbel R, Sykes BD, Rowe BH, Adamko DJ. 2011

Metabolomic Profiling Pediatric Asthma: the Diagnostic Utility of Urine NMR

Journal of Allergy and Clinical Immunology

Blimkie D, Fortuno ES, Yan H, Cho P, Ho K, Turvey SE, Marchant A, Goriely S, Kollman TR. 2011

Variables to be controlled in the assessment of blood innate immune responses to Toll-like receptor stimulation

Journal of Immunological Methods

Maltby S, Freeman S, Gold M, Baker JHE, Zybtnuik L, Minchinton AI, Gold MR, Roskelley CD, McNagny KM. 2011

Opposing roles for CD34 in tumor growth alter early stage vascular and late stage immune cell infiltration


Rousseau M-C, Boulay M-E, Goronfolah L, Denburg J, Keith P, Boulet L-P. 2011

Comparative responses to nasal allergen challenge in allergic rhinitic subjects with or without asthma

Allergy, Asthma & Clinical Immunology

Hackett TL, Singhera GK, Shaheen F, Hayden P, Jackson GR, Hegele RG, Van Eeden S, Dorscheid DR, Knight DA, Bai T. 2011

Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to RSV and air pollution

American Journal of Respiratory Cell and Molecular Biology

Tam A, Morrish D, Wadsworth S, Dorscheid DR, Man SP, Sin DD. 2011

The role of female hormones on lung function in chronic lung diseases

BMC Women’s Health

Blanchet MR, Bennett JL, Gold M, Levantini E, Tenen DG, Girard M, Cormier Y, McNagny KM. 2011

CD34 is required for dendritic cell trafficking and pathology in lung inflammatory disease

American Journal of Respiratory and Critical Care Medicine

Ilarraza R, Wu Y, Davione F, Ebeling C, Adamko DJ. 2011

Human dendritic cells promote an antiviral immune response when stimulated by CVT-E002

Journal of Pharmacology and Experimental Therapeutics

Arizmendi NG, Abel M, Puttagunta L, Asaduzzaman M, Davidson C, Karimi K, Forsythe P, Vliagoftis H. 2011

Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation

Allergy, Asthma & Clinical Immunology

Forsythe P. 2011

Probiotics and lung diseases


Ito J, Harada N, Nagashima O, Makino F, Usui Y, Yagita H, Okumura K, Dorscheid DR, Atsuta R, Akiba H, Takahashi K. 2011

Wound-induced TGF-β1 and TGF-β2 enhance airway epithelial repair via HB-EGF and TGF-α

Biochemical and Biophysical Research Communication

Sohani ZN, Strinich TX, Watson B, Smith SG, Torek A, Howie KJ, Gaurvreau GM. 2011

Reproducibility of sputum differential cell counts is not affected by squamous epithelial cells

Journal of Asthma

Birger N, Gould T, Stewart J, Miller MR, Larson T, Carlsten C. 2011

Air pollution Exposure Laboratory (APEL) for controlled human exposure to diesel exhaust and other inhalants: characterization and comparison to existing facilities

Inhalation Toxicology

MacRedmond R, Dorsheid DR. 2011

Conjugated linoleic acid (CLA): is it time to supplement asthma therapy?

Pulmonary Pharmacology & Therapeutics

Wadsworth SJ, Sin DD, Dorscheid DR. 2011

Clinical update on the use of biomarkers of airway inflammation in the management of asthma

Journal of Asthma and Allergy

Blanchet MR, Gold M, Maltby M, Bennett J, Lee DM, McNagny KM 2010

Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability

The Journal of Immunology

Naus S, Blanchet NS, Gossens K, Zaph C, Bartsch J, McNagny KM, and Ziltener HJ. 2010

The metalloprotease, ADAM8, is essential for the development of experimental asthma

American Journal of Respiratory and Critical Care Medicine

Ellis A, Ackerman S, Crawford L, Du J, Bedi R, Denburg J. 2010

Cord blood molecular biomarkers of eosinophilopoiesis: kinetic analysis of GATA-1, MBP1 and IL-5Ra mRNA expression

Pediatric Allergy and Immunology

Wadsworth SJ, Atsuta R, McIntyre JO, Hackett TL, Singhera GK, Dorscheid DR. 2010

Interleukin-13 and TH2 cytokine exposure triggers matrix metalloproteinase-7 mediated Fas ligand cleavage from bronchial epithelial cells

Journal of Allergy and Clinical Immunology

Maltby S, Wohlfarth C, Gold M, Zybtnuik L, Hughes MR, McNagny KM. 2010

CD34 is required for infiltration of eosinophils into the colon during DSS-induced ulcerative colitis

American Journal of Pathology

Grassl G, Faustmann M, Gill N, Zybtnuik L, Merkens H, So L, McNagny KM, Finlay BB. 2010

CD34 mediates intestinal inflammation in Salmonella-infected mice

Cellular Microbiology

Allakhverdieva Z, Comeau MR, Delespesse G. 2010

Dexamethasone regulation of thymic stromal lymphopoietin receptor expression on mast cells and their precursors

Journal of Allergy and Clinical Immunology

Marchant D, Singhera GK, Utokaparch S, Boyd JH, Luo Z, Si X, Dorscheid DR, McManus BM, Hegele RG. 2010

Toll-like receptor 4 mediated p38 mitogen activated protein kinase activation is a determinant of respiratory virus entry and tropism

Journal of Virology

MacRedmond R, Singhera G, Attridge S, Bahzad M, Fava C, Lai Y, Hallstrand TS, Dorscheid DR. 2010

Conjugated linoleic acid improves airway hyper-reactivity in overweight mild asthmatics

Clinical & Experimental Allergy

Gaurvreau GM, Boulet LP, Cockcroft DW, FitzGerald JM, Carlsten C, Davis BE, Deschesnes F, Duong M, Durn BL, Howie KJ, Hui L, Kasaian MT, Killian KJ, Strinich TX, Watson RM, Zhou S, Raible D, O'Byrne PM. 2010

Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma

American Journal of Respiratory and Critical Care Medicine

Corbett N, Blimkie D, Ho K, Cai B, Sutherland D, Kallos A, Crabtree J, Rein-Watson A, Lavoie PM, Turvey SE, Hawkins NR, Self SG, Wilson CB, Hajjar AM, Fortuno ES, Kollmann TR. 2010

Ontogeny of the innate immune response to TLR stimulation


Mathison RD, Davison JS, Befus AD,Gingerich DA. 2010

Salivary gland-derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein

Journal of Inflammation

Allaverdian S, Wang A, Singhera GK, Wong BW, Dorscheid DR. 2009

Sialyl Lewis X modification of the epidermal growth factor receptor regulates function during airway epithelial wound repair

Clinical & Experimental Allergy

Maltby S, Khazaie K, McNagny K. 2009

Mast cells in tumor growth: angiogenesis, tissue remodeling and immune-modulation

Biochimica et Biophysica Acta (BBA) – Reviews on Cancer

Morris KE, St. Laurent CD, Hoeve RS, Forsythe P, Mathsion R, Suresh M, Befus AD. 2009

Autonomic nervous system regulates secretion of anti-inflammatory prohormone SMR1 from rat salivary glands

American Journal of Physiology – Cell Physiology