Legacy Project
Research Leaders:
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 |
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| Dr. Paul O’Byrne, Professor, Div. of Respirology, Dept. of Medicine & Dean and Vice-President, Faculty of Health Sciences, McMaster University
Director, Allergic Asthma CIC |
Dr. Gail Gauvreau, Professor, Division of Respirology, Department of Medicine, McMaster University
Co-Director, Allergic Asthma CIC |
Dr. Parameswaran Nair, Frederick E. Hargreave Teva Innovation Chair in Airway Diseases & Professor, Div. of Respirology, Dept. of Medicine, McMaster University
Severe Asthma CIC |
Strategic Focus:
This multi-centre, Canadian-based Phase II clinical trials group fast-tracks early-stage potential drug candidates for allergic asthma, severe asthma and allergic rhinitis to accelerate the development of new therapies for allergic disease.
CIC Publications
CIC Website
Recent high-profile publications:
- New England Journal of Medicine: September 25, 2014
- Science Translational Medicine: 2 July 2014
- New England Journal of Medicine: May 19, 2014
Projects:
| Project | Term | Investigators |
|---|---|---|
|
CIC Quality Assurance Plan |
2008 - 2012 |
O’Byrne, Paul |
|
CIC Quality Assurance Plan Statistical Analyses |
2010 - 2012 |
O’Byrne, Paul |
|
Development of a Microarray Genotyping Chip for Clinical Trials |
2007 - 2009 |
Abugharbieh, Rafeed; Gauvreau, Gail; Hudson, Thomas; O’Byrne, Paul; Sandford, Andrew; Tebbutt, Scott; Wilkinson, Mark; Zamar, Ruben |
|
Functional genomic and proteomic changes in response to nasal allergen challenge and following peptide immunotherapy treatment of the same: A partnership with the Allergic-Rhinitis Clinical Investigator Collaborative (AR-CIC) and industry (Success Stories profile) |
2010 - 2012 |
Adamko, Darryl; Ellis, Anne; Hickey, Pascal; Larche, Mark; Neighbour, Helen; Tebbutt, Scott; Wilson-McManus, Janet |
|
Proposed Severe Asthma Network |
2007 - 2009 |
Vethanayagam, Dilini |
|
The Clinical Investigator Collaborative (CIC)-Allergic Asthma (AA) |
2012 - 2016 |
Adamko, Darryl; Boulet, Louis-Philippe; Chakir, Jamila; Cockcroft, Don; Dahlen, Barbro; FitzGerald, Mark; Gauvreau, Gail; Leigh, Richard; Mayers, Irvin; O’Byrne, Paul; Tebbutt, Scott; Davis, Beth; Sehmi, Roma |
|
The Clinical Investigator Collaborative (CIC)-Allergic Rhinitis (AR) (Success Stories profile) |
2012 - 2016 |
Adamko, Darryl; Boulet, Louis-Philippe; Ellis, Anne; Keith, Paul; Larché, Mark; Neighbour, Helen; Tebbutt, Scott; Vliagoftis, Harissios; Waserman, Susan |
|
The Clinical Investigator Collaborative (CIC)-Severe Asthma |
2012 - 2016 |
Boulet, Louis-Philippe; Dorscheid, Del; FitzGerald, Mark; Leigh, Richard; Lemiére, Catherine; Martin, James; Nair, Parameswaran |
|
Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC): Development of a standardized nasal allergen challenge model for a multi-center research collaborative to investigate novel therapeutic agents for allergic rhinitis (Success Stories profile) |
2010 - 2012 |
Boulet, Louis-Philippe; Ellis, Anne; Keith, Paul; Neighbour, Helen; Ratz, Jodan; Vliagoftis, Harissios; Waserman, Susan |
|
Clinical Investigator Collaborative (CIC) (Success Stories profile) |
2007 - 2012 |
Befus, Dean; Bhutani, Mohit; Boulet, Louis-Philippe; Carlsten, Chris; Chakir, Jamila; Cockcroft, Don; Cormier, Yvon; Cote, Johanne; Cowie, Robert; Dahlen, Barbro; Dahlen, Sven-Erik; Dourado, Carlos; Field, Stephen; FitzGerald, Mark; Furci, Patrizia; Gauvreau, Gail; Hodges, Michael; Larché, Mark; Laviolette, Michel; Leigh, Richard; Martin, Joel; Matthews, John; Mayers, Irvin; O’Byrne, Paul; Tebbutt, Scott; Tiberi, Jean-Jacques; Vethanayagam, Dilini |